For decades, acne treatment has largely followed two familiar paths: topical treatments that target bacteria and exfoliate the skin, or oral medications that regulate hormones but may come with systemic side effects.
Now, a new option is changing the landscape.
Winlevi® (clascoterone 1% cream) represents a significant breakthrough, offering a targeted, topical approach to treating acne at its hormonal source.
What is Winlevi?
Winlevi is a prescription-only topical treatment designed for acne vulgaris in adults and adolescents aged 12 and over.
Unlike traditional treatments, it contains clascoterone, a compound that works directly on the skin to address one of the root causes of acne: excess oil production driven by hormones.
Why is Winlevi Different?
Most acne treatments fall into one of two categories:
- Topical treatments e.g. retinoids, benzoyl peroxide, that target bacteria or skin turnover
- Oral medications e.g. antibiotics, oral contraception, that act systemically
Winlevi introduces a third approach.
It is the first topical acne treatment in nearly 40 years to use a completely new mechanism of action. It targets hormonal activity directly in the skin.
How Does Winlevi Work?
Acne is often driven by androgens (hormones such as testosterone), which stimulate the skin’s oil glands.
Winlevi works by:
- Blocking androgen receptors in the skin
- Reducing sebum (oil) production
- Decreasing inflammation and breakouts
By interrupting this hormonal signal at the skin level, Winlevi helps prevent clogged pores and reduces acne formation.
Who is Winlevi Suitable For?
Winlevi is a versatile treatment option for:
- Hormonal acne e.g. jawline or chin breakouts
- Oily skin prone to congestion
- Patients who prefer to avoid oral medication
- Both men and women aged 12+
Because it is applied topically and broken down quickly in the skin, it avoids many of the systemic side effects associated with oral therapies.
What Results Can You Expect?
Clinical studies have shown that treatments containing clascoterone can significantly reduce acne lesions, with improvements typically seen over several weeks of consistent use.
As with most acne treatments, results improve with time and adherence, and your clinician may recommend combining it with other therapies for optimal outcomes.
How is Winlevi Used?
- Applied twice daily in the morning and evening
- Used on clean, dry skin
- Prescription and supervision by a qualified doctor is required
Are There Any Side Effects?
Winlevi is generally well tolerated. The most common side effects are mild and may include:
- Redness
- Dryness
- Itching or irritation at the application site
Your clinician will advise whether it is suitable for your skin type and condition.
The Future of Acne Treatment
Winlevi marks an important step forward in dermatology, offering a targeted, non-systemic option that bridges the gap between traditional topical treatments and oral medications.
For many patients, this means:
- More personalised treatment plans
- Fewer systemic side effects
- Better control of hormonally driven acne
Discover Personalised Acne Treatment at Oxona Healthcare
At Oxona Healthcare, we understand that acne is complex and deeply personal. Our clinicians offer tailored treatment plans, combining the latest medical innovations like Winlevi with expert skincare guidance.
Book a consultation today to find the right treatment for your skin.